Ibutilide

Ibutilide prolongs repolarization by inhibition of the delayed rectifier potassium current (Ikr) and by selective enhancement of the slow inward sodium current. Ibutilide is a newer anti arrhythmic used in particularly for patients suffering from atrial fibrillation not responding to the commonly used medications. Ibutilide is efficacious in the termination of atrial fibrillation (AF) and flutter with both single and repeated intravenous infusions. It […]