Angiotensin Receptor Blockers

The pharmacology of losartan and other angiotensin receptor blockers (ARBs) is very important. In a dose of 50 mg/day losartan is an effective antihypertensive. Action manifests early and progresses to peak at 2-4 weeks. Addition of 12.5 mg/day hydrochlorothiazide further enhances the fall in BP. The newer ARBs—valsartan, candesartan, irbesartan and telmisartan have been shown […]