Ibutilide

Ibutilide prolongs repolarization by inhibition of the delayed rectifier potassium current (Ikr) and by selective enhancement of the slow inward sodium current. Ibutilide is a newer anti arrhythmic used in particularly for patients suffering from atrial fibrillation not …

Dofetilide

Dofetilide prolongs the action potential and QTC in a concentration-related manner. Dofetilide exerts its effects solely by inhibition of the rapid component of the delayed rectifier potassium current Ikr. …

Human albumin

Human albumin is obtained from pooled human plasma; 100 ml of 20% human albumin solution is the osmotic equivalent of about 400 ml of fresh frozen plasma or 800 …

Fibrates

The fibrates (isobutyric acid derivatives) primarily activate lipoprotein lipase which is a key enzyme in the degradation of VLDL resulting in lowering of circulating TGs. This effect is of …

Fenofibrate

Fenofibrate is another 2nd generation prodrug fibric acid derivative which has greater HDL-CH raising and greater LDL-CH lowering action than other fibrates. Hence Fenofibrate may be more appropriate as …

Bezafibrate

Bezafibrate is a second generation fibric acid derivative and is used to lower cholesterol levels. It is an alternative for gemfibrozil in mixed hyperlipidaemias (type III, IV and V). …

Minoxidil

Minoxidil is a powerful vasodilator, the pattern of action resembling hydralazine, i.e. direct relaxation of arteriolar smooth muscle with little effect on venous capacitance. Marked vasodilatation elicits strong compensatory …

Nipride medication

Nipride medication is a rapidly (within seconds) and consistently acting vasodilator; has brief duration of action (2-5 min)—vascular tone can be titrated with the rate of i.v. infusion. It …

Indapamide

Indapamide is a mild diuretic, chemically related to chlorthalidone; reduces BP at doses which cause little diuresis. Electrolyte disturbances and K loss are minimal at antihypertensive doses. In post-stroke …