Hydroxyethyl starch also called HES or Hetastarch is a complex mixture of ethoxylated amylopectin of various molecular sizes; average MW 4.5 lac (range 10,000 to 1 million). The colloidal properties of 6% HES approximate those of human albumin. Plasma volume expands slightly in excess of the volume infused. This happens as extra vascular fluid is […]
Degraded gelatin polymer or Polygeline is a polypeptide with average MW 30,000 which exerts oncotic pressure similar to albumin and is not that antigenic. www.copy-swiss.me Hypersensitivity reactions are rare with Polygeline, but should watched for. It is a colloid, which is a type of fluid heavier than the commonly used fluids that are called crystalloids.
Lovenox is an anticoagulant commonly in use. It is the commercial name for Enoxaparin and is produced by Sanofi-Aventis. Lovenox is treatment of deep venous thrombosis ( DVT) and Pulmonary embolism. It is recently been prescribed tretment as well as prevention of acute coronary syndromes like unstable angina. Lovenox is a low molecular weight heparin used to prevent blood
Anxiety is a common symptom that many feel on certain occasions like facing an exam or addressing a speech or even visiting the doctor or getting a procedure being done. Drugs that decrease anxiety are called as anxiolytic medications. They are commonly prescribed by doctors for a variety of problems like insomnia, panic attacks and
Amiodarone is a complex antiarrhythmic agent (predominantly class III) that shares at least some of the properties of each of the other three Vaughn-Williams classes of antiarrhythmics. Atrial fibrillation is a common arrhythmia in the intensive care unit (ICU) setting. The mainstay of therapy is rate control, with beta-blockers being the first-line agent. However, frequently
Agents that can be considered as Amiodarone alternatives for the treatment of atrial fibrillation depend upon the patient’s cardiac history, as individuals with reduced left ventricular systolic function are especially prone to the proarrhythmic effects of certain antiarrhythmic agents. Some commonly used Amiodarone alternatives include ibutilide, dofetilide, and sotalol. Strong consideration should be made for
Ibutilide prolongs repolarization by inhibition of the delayed rectifier potassium current (Ikr) and by selective enhancement of the slow inward sodium current. Ibutilide is a newer anti arrhythmic used in particularly for patients suffering from atrial fibrillation not responding to the commonly used medications. Ibutilide is efficacious in the termination of atrial fibrillation (AF) and flutter with both single and repeated intravenous infusions. It
Dofetilide prolongs the action potential and QTC in a concentration-related manner. Dofetilide exerts its effects solely by inhibition of the rapid component of the delayed rectifier potassium current Ikr. Dofetilide has stronger evidence in its favor for acute cardioversion of atrial fibrillation than for maintenance thereafter, according to a meta-analysis. It can be given to
